Western blot analysis of tissue extracts with PDPN polyclonal antibody (Cat # PAB19505). Lane 1, mouse liver tissue lysate. Lane 2, mouse brain tissue lysate. Lane 3, mouse kidney tissue lysate. Lane 4, mouse spleen tissue lysate. Lane 5, mouse thymus tissue lysate. Lane 6, mouse lung tissue lysate. Lane 7, mouse ovarian tissue lysate.
This gene encodes a type-I integral membrane glycoprotein with diverse distribution in human tissues. The physiological function of this protein may be related to its mucin-type character. The homologous protein in other species has been described as a differentiation antigen and influenza-virus receptor. The specific function of this protein has not been determined but it has been proposed as a marker of lung injury. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq
OTTHUMP00000009640,OTTHUMP00000044504,glycoprotein, 36-KD,hT1alpha-1,hT1alpha-2,lung type I cell membrane associated glycoprotein,lung type-I cell membrane-associated glycoprotein,lung type-I cell membrane-associated glycoprotein (T1A-2)