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Last updated: 2016/10/23
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TBX1 polyclonal antibody

  • Catalog # : PAB17338
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of TBX1.
  • Immunogen:
  • A synthetic peptide corresponding to C-terminus of human TBX1.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Specificity:
  • This antibody detects endogenous levels of total TBX1 protein.
  • Form:
  • Liquid
  • Recommend Usage:
  • Western Blot (1:500-1:1000)
    Immunofluorescence (1:500-1:1000)
    ELISA (1:20000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.4 (150mM NaCl, 0.02% sodium azide, 50% glycerol)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • 1.
  • The consensus coding sequences of human breast and colorectal cancers.
    Sjoblom T, Jones S, Wood LD, Parsons DW, Lin J, Barber TD, Mandelker D, Leary RJ, Ptak J, Silliman N, Szabo S, Buckhaults P, Farrell C, Meeh P, Markowitz SD, Willis J, Dawson D, Willson JK, Gazdar AF, Hartigan J, Wu L, Liu C, Parmigiani G, Park BH, Bachman KE, Papadopoulos N, Vogelstein B, Kinzler KW, Velculescu VE.Science. 2006 Oct 13;314(5797):268-74. Epub 2006 Sep 7.
  • 2.
  • Role of TBX1 in human del22q11.2 syndrome.
    Yagi H, Furutani Y, Hamada H, Sasaki T, Asakawa S, Minoshima S, Ichida F, Joo K, Kimura M, Imamura S, Kamatani N, Momma K, Takao A, Nakazawa M, Shimizu N, Matsuoka R.Lancet. 2003 Oct 25;362(9393):1366-73.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis of extracts from COLO 205 cells, using TBX1 polyclonal antibody (Cat # PAB17338).
    Peptide "+" means "with peptide blocking".
  • Immunofluorescence
  • Immunofluorescence
  • Immunofluorescence analysis of A-549 cells, using TBX1 polyclonal antibody (Cat # PAB17338).
    Peptide "+" means "with peptide blocking".
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 6899
  • Gene Name:
  • TBX1
  • Gene Alias:
  • Gene Description:
  • T-box 1
  • Gene Summary:
  • This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene product shares 98% amino acid sequence identity with the mouse ortholog. DiGeorge syndrome (DGS)/velocardiofacial syndrome (VCFS), a common congenital disorder characterized by neural-crest-related developmental defects, has been associated with deletions of chromosome 22q11.2, where this gene has been mapped. Studies using mouse models of DiGeorge syndrome suggest a major role for this gene in the molecular etiology of DGS/VCFS. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq
  • Other Designations:
  • T-box 1 transcription factor C,Testis-specific T-box protein,brachyury
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