TBX1 polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of COLO 205 cell lysate with TBX1 polyclonal antibody (Cat # PAB24875).
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of TBX1.
Immunogen
A synthetic peptide corresponding to TBX1.
Host
Rabbit
Theoretical MW (kDa)
43
Reactivity
Human
Specificity
TBX1 polyclonal antibody detects endogenous levels of TBX1 protein.
Form
Liquid
Purification
Antigen affinity purification
Concentration
1 mg/mL
Purity
> 95% by SDS-PAGE
Recommend Usage
Western Blot (1:500-1:1000)
Immunohistochemistry (1:50-1:200)
Immunofluorescence (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In 1x PBS, pH 7.2 (0.05% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of COLO 205 cell lysate with TBX1 polyclonal antibody (Cat # PAB24875).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunofluorescence
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Gene Info — TBX1
Entrez GeneID
6899Gene Name
TBX1
Gene Alias
CAFS, CTHM, DGCR, DGS, DORV, TBX1C, TGA, VCFS
Gene Description
T-box 1
Gene Ontology
HyperlinkGene Summary
This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene product shares 98% amino acid sequence identity with the mouse ortholog. DiGeorge syndrome (DGS)/velocardiofacial syndrome (VCFS), a common congenital disorder characterized by neural-crest-related developmental defects, has been associated with deletions of chromosome 22q11.2, where this gene has been mapped. Studies using mouse models of DiGeorge syndrome suggest a major role for this gene in the molecular etiology of DGS/VCFS. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq
Other Designations
T-box 1 transcription factor C|Testis-specific T-box protein|brachyury
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Interactome
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Disease
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