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TREX1 polyclonal antibody

  • Catalog # : PAB16681
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of TREX1.
  • Immunogen:
  • A synthetic peptide corresponding to internal region 15 amino acids of human TREX1.
  • Host:
  • Rabbit
  • Reactivity:
  • Human, Mouse, Rat
  • Form:
  • Liquid
  • Recommend Usage:
  • Western Blot (1-2 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.02% sodium azide)
  • Storage Instruction:
  • Store at 4°C for three months. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • Western blot analysis of TREX1 in human spleen tissue lysate with TREX1 polyclonal antibody (Cat # PAB16681) at (A) 0.5 ug/mL and (B) 1 ug/mL .
  • Immunohistochemistry
  • Immunohistochemistry
  • Immunohistochemistry of TREX1 in human spleen tissue with TREX1 polyclonal antibody (Cat # PAB16681) at 2.5 ug/mL .
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • Gene Information
  • Gene Name:
  • TREX1
  • Gene Alias:
  • Gene Description:
  • three prime repair exonuclease 1
  • Gene Summary:
  • This gene encodes the major 3'->5' DNA exonuclease in human cells. The protein is a non-processive exonuclease that may serve a proofreading function for a human DNA polymerase. It is also a component of the SET complex, and acts to rapidly degrade 3' ends of nicked DNA during granzyme A-mediated cell death. Mutations in this gene result in Aicardi-Goutieres syndrome, chilblain lupus, and Cree encephalitis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • 3' repair exonuclease 1,OTTHUMP00000164813,deoxyribonuclease III, dnaQ/mutD-like
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