TREX1 recombinant monoclonal antibody, clone R05-1D6
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More Files
- More Functions
Western Blot
Western blot analysis of TREX1 in Hela lysates using human TREX1 recombinant monoclonal antibody, clone R05-1D6 (Cat # RAB01714).
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human breast cancer with TREX1 recombinant monoclonal antibody, clone R05-1D6 (Cat # RAB01714). High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
Immunocytochemistry
Immunocytochemistry analysis of TREX1 (green) in Hela using human TREX1 recombinant monoclonal antibody, clone R05-1D6 (Cat # RAB01714), and DAPI(blue).
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human TREX1.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against recombinant protein corresponding to human TREX1
Theoretical MW (kDa)
Calculated MW: 33 kD
Reactivity
Human
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Immunofluorescence (1:50-1:200)
Immunohistochemistry (1:50-1:100)
Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In 50 mM Tris-Glycine, pH 7.4 (0.15 M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA)
Storage Instruction
Store at 4°C for short term. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western blot analysis of TREX1 in Hela lysates using human TREX1 recombinant monoclonal antibody, clone R05-1D6 (Cat # RAB01714).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human breast cancer with TREX1 recombinant monoclonal antibody, clone R05-1D6 (Cat # RAB01714). High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.Immunohistochemistry (Frozen sections)
Immunocytochemistry
Immunocytochemistry analysis of TREX1 (green) in Hela using human TREX1 recombinant monoclonal antibody, clone R05-1D6 (Cat # RAB01714), and DAPI(blue). -
Gene Info — TREX1
Entrez GeneID
11277Protein Accession#
Q9NSU2Gene Name
TREX1
Gene Alias
AGS1, AGS5, CRV, DKFZp434J0310, DRN3, HERNS
Gene Description
three prime repair exonuclease 1
Gene Ontology
HyperlinkGene Summary
This gene encodes the major 3'->5' DNA exonuclease in human cells. The protein is a non-processive exonuclease that may serve a proofreading function for a human DNA polymerase. It is also a component of the SET complex, and acts to rapidly degrade 3' ends of nicked DNA during granzyme A-mediated cell death. Mutations in this gene result in Aicardi-Goutieres syndrome, chilblain lupus, and Cree encephalitis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
3' repair exonuclease 1|OTTHUMP00000164813|deoxyribonuclease III, dnaQ/mutD-like
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Interactome
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Disease
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