PDGFA polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against PDGFA.
Immunogen
Human PDGFA.
Sequence
VKRCTGCCNTSSVKCQPSRVHHRSVKVAKVEYVRKKPKLKEVQVR
Host
Rabbit
Reactivity
Human, Mouse, Rat
Form
Lyophilized
Isotype
IgG
Recommend Usage
ELISA (1-2 ug/mL)
Western Blot (2-10 ug/mL)
Immunohistochemistry (2-10 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
Lyophilized from PBS, pH 7.4.
Storage Instruction
The lyophilized antibody is stable for at least 1 year from date of receipt at -20°C.
After reconstitution with 0.01 M PBS, pH 7.4 or other diluents, this antibody can be stored in working aliquots at 2°C- 8°C for one month, or at -20°C for six months without detectable loss of activity.
Aliquot to avoid repeated freezing and thawing. -
Applications
Western Blot
Immunohistochemistry
Enzyme-linked Immunoabsorbent Assay
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Gene Info — PDGFA
Entrez GeneID
5154Protein Accession#
P04085Gene Name
PDGFA
Gene Alias
PDGF-A, PDGF1
Gene Description
platelet-derived growth factor alpha polypeptide
Omim ID
173430Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. This gene product can exist either as a homodimer or as a heterodimer with the platelet-derived growth factor beta polypeptide, where the dimers are connected by disulfide bonds. Studies using knockout mice have shown cellular defects in oligodendrocytes, alveolar smooth muscle cells, and Leydig cells in the testis; knockout mice die either as embryos or shortly after birth. Two splice variants have been identified for this gene. [provided by RefSeq
Other Designations
PDGF A-chain|platelet-derived growth factor alpha|platelet-derived growth factor alpha chain|platelet-derived growth factor alpha isoform 2 preproprotein
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