KCNQ5 polyclonal antibody
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Specification
Product Description
Goat polyclonal antibody raised aganist synthetic peptide of KCNQ5.
Immunogen
A synthetic peptide corresponding to human KCNQ5.
Sequence
C-ESTDALSLPHVKLK
Host
Goat
Theoretical MW (kDa)
102
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Recommend Usage
ELISA (1:64000)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Enzyme-linked Immunoabsorbent Assay
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Gene Info — KCNQ5
Entrez GeneID
56479Protein Accession#
NP_062816.2Gene Name
KCNQ5
Gene Alias
Kv7.5
Gene Description
potassium voltage-gated channel, KQT-like subfamily, member 5
Omim ID
607357Gene Ontology
HyperlinkGene Summary
This gene is a member of the KCNQ potassium channel gene family that is differentially expressed in subregions of the brain and in skeletal muscle. The protein encoded by this gene yields currents that activate slowly with depolarization and can form heteromeric channels with the protein encoded by the KCNQ3 gene. Currents expressed from this protein have voltage dependences and inhibitor sensitivities in common with M-currents. They are also inhibited by M1 muscarinic receptor activation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000016729|OTTHUMP00000064152|OTTHUMP00000064153|potassium channel protein
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Interactome
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Disease
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Publication Reference
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Regulation of the voltage-gated K(+) channels KCNQ2/3 and KCNQ3/5 by serum- and glucocorticoid-regulated kinase-1.
Schuetz F, Kumar S, Poronnik P, Adams DJ.
American Journal of Physiology. Cell Physiology 2008 Jul; 295(1):C73.
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Regulation of the voltage-gated K(+) channels KCNQ2/3 and KCNQ3/5 by serum- and glucocorticoid-regulated kinase-1.
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