KCNQ5 monoclonal antibody (M01), clone 2E2
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant KCNQ5.
Immunogen
KCNQ5 (NP_062816, 833 a.a. ~ 932 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
QNLIRSTEELNIQLSGSESSGSRGSQDFYPKWRESKLFITDEEVGPEETETDTFDAAPQPAREAAFASDSLRTGRSRSSQSICKAGESTDALSLPHVKLK
Host
Mouse
Reactivity
Human
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.74 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of KCNQ5 expression in transfected 293T cell line by KCNQ5 monoclonal antibody (M01), clone 2E2.
Lane 1: KCNQ5 transfected lysate (Predicted MW: 46.9 KDa).
Lane 2: Non-transfected lysate.
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged KCNQ5 is approximately 0.1ng/ml as a capture antibody.ELISA
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Gene Info — KCNQ5
Entrez GeneID
56479GeneBank Accession#
NM_019842Protein Accession#
NP_062816Gene Name
KCNQ5
Gene Alias
Kv7.5
Gene Description
potassium voltage-gated channel, KQT-like subfamily, member 5
Omim ID
607357Gene Ontology
HyperlinkGene Summary
This gene is a member of the KCNQ potassium channel gene family that is differentially expressed in subregions of the brain and in skeletal muscle. The protein encoded by this gene yields currents that activate slowly with depolarization and can form heteromeric channels with the protein encoded by the KCNQ3 gene. Currents expressed from this protein have voltage dependences and inhibitor sensitivities in common with M-currents. They are also inhibited by M1 muscarinic receptor activation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000016729|OTTHUMP00000064152|OTTHUMP00000064153|potassium channel protein
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Interactome
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Disease
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