ITPKC polyclonal antibody
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More Files
- More Functions
Western Blot (Tissue lysate)
ITPKC polyclonal antibody (Cat # PAB15634) (1 ug/mL) staining of human pancreas lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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Specification
Product Description
Goat polyclonal antibody raised aganist synthetic peptide of ITPKC.
Immunogen
A synthetic peptide corresponding to amino acids at internal region of human ITPKC.
Sequence
C-ETERPKQKTEPDRSS
Host
Goat
Theoretical MW (kDa)
75.2
Reactivity
Human
Specificity
Approximately 75 KDa band observed in human pancreas lysates (calculated MW of 75.2 KDa according to NP_079470.1).
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Recommend Usage
ELISA (1:2000)
Western Blot (1-3 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
ITPKC polyclonal antibody (Cat # PAB15634) (1 ug/mL) staining of human pancreas lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.Enzyme-linked Immunoabsorbent Assay
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Gene Info — ITPKC
Entrez GeneID
80271Protein Accession#
NP_079470.1Gene Name
ITPKC
Gene Alias
IP3KC
Gene Description
inositol 1,4,5-trisphosphate 3-kinase C
Omim ID
606476Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the inositol 1,4,5-trisphosphate [Ins(1,4,5)P(3)] 3-kinase family of enzymes that catalyze the phosphorylation of inositol 1,4,5-trisphosphate to 1,3,4,5-tetrakisphosphate. The encoded protein is localized to the nucleus and cytoplasm and has both nuclear import and nuclear export activity. Single nucleotide polymorphisms in this gene are associated with Kawasaki disease
Other Designations
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Interactome
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Disease
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Publication Reference
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ITPKC functional polymorphism associated with Kawasaki disease susceptibility and formation of coronary artery aneurysms.
Onouchi Y, Gunji T, Burns JC, Shimizu C, Newburger JW, Yashiro M, Nakamura Y, Yanagawa H, Wakui K, Fukushima Y, Kishi F, Hamamoto K, Terai M, Sato Y, Ouchi K, Saji T, Nariai A, Kaburagi Y, Yoshikawa T, Suzuki K, Tanaka T, Nagai T, Cho H, Fujino A, Sekine A, Nakamichi R, Tsunoda T, Kawasaki T, Nakamura Y, Hata A.
Nature Genetics 2008 Jan; 40(1):35.
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ITPKC functional polymorphism associated with Kawasaki disease susceptibility and formation of coronary artery aneurysms.
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