BCL6 polyclonal antibody
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More Files
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Specification
Product Description
Rabbit Polyclonal antibody raised against synthetic peptide of BCL6.
Immunogen
A synthetic peptide corresponding to C-terminus of human BCL6.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Specificity
Detects Bcl-6 from human, mouse and rat.
Form
Liquid
Recommend Usage
Immunoprecipitation (5-10 ug/mL)
Western Blot (1-4 ug/mL)
Immunohistochemistry (Frozen sections) (20-40 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (50% glycerol, BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C. For long term storage store at -80°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Immunohistochemistry (Frozen sections)
Immunoprecipitation
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Gene Info — BCL6
Entrez GeneID
604Gene Name
BCL6
Gene Alias
BCL5, BCL6A, LAZ3, ZBTB27, ZNF51
Gene Description
B-cell CLL/lymphoma 6
Omim ID
109565Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of START-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq
Other Designations
B-cell lymphoma 6 protein|B-cell lymphoma 6 protein transcript|cys-his2 zinc finger transcription factor|lymphoma-associated zinc finger gene on chromosome 3|zinc finger protein 51|zinc finger transcription factor BCL6S
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Interactome
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Disease
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