BCL6 recombinant monoclonal antibody, clone 6E3
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More Files
- More Functions
Immunohistochemistry
Immunohistochemistry image of BCL6 recombinant monoclonal antibody, clone 6E3 diluted at 1:33 and staining in paraffin-embedded human testis tissue performed on a Leica BondTM system.
Flow Cytometry
Overlay Peak curve showing Jurkat cells stained with BCL6 recombinant monoclonal antibody, clone 6E3 (red line) at 1:50.
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human BCL6.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against a synthetic peptide corresponding to human BCL6.
Reactivity
Human
Form
Liquid
Purification
Affinity chromatography purification
Isotype
IgG
Recommend Usage
ELISA
Flow Cytometry(1:50-1:200)
Immunohistochemistry(1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH7.4 (150 mM NaCl, 0.02% sodium azide and 50% glycerol)
Storage Instruction
Store at -20°C or -80°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry
Immunohistochemistry image of BCL6 recombinant monoclonal antibody, clone 6E3 diluted at 1:33 and staining in paraffin-embedded human testis tissue performed on a Leica BondTM system.Enzyme-linked Immunoabsorbent Assay
Flow Cytometry
Overlay Peak curve showing Jurkat cells stained with BCL6 recombinant monoclonal antibody, clone 6E3 (red line) at 1:50. -
Gene Info — BCL6
Entrez GeneID
604Protein Accession#
P41182Gene Name
BCL6
Gene Alias
BCL5, BCL6A, LAZ3, ZBTB27, ZNF51
Gene Description
B-cell CLL/lymphoma 6
Omim ID
109565Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of START-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq
Other Designations
B-cell lymphoma 6 protein|B-cell lymphoma 6 protein transcript|cys-his2 zinc finger transcription factor|lymphoma-associated zinc finger gene on chromosome 3|zinc finger protein 51|zinc finger transcription factor BCL6S
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Interactome
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Disease
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