SETD8 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against full length recombinant SETD8.
Immunogen
Recombinant Flag (N-terminus) and His (C-terminus) fusion protein corresponding to full length human SETD8.
Host
Rabbit
Reactivity
Human, Mouse
Form
Liquid
Recommend Usage
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.05% sodium azide, 0.05% proclin 300)
Storage Instruction
Store at -20°C. For long term storage store at -80°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot was performed on HeLa nuclear extract (HeLa NE, 20 ug) using SETD8 polyclonal antibody (Cat # PAB14114) at dilution 1 : 1000 in TBS-Tween + 5% skimmed milk. -
Gene Info — SETD8
Entrez GeneID
387893Protein Accession#
Q9NQRGene Name
SETD8
Gene Alias
KMT5A, PR-Set7, SET07, SET8
Gene Description
SET domain containing (lysine methyltransferase) 8
Omim ID
607240Gene Ontology
HyperlinkOther Designations
H4-K20-specific histone methyltransferase|PR/SET domain containing protein 8|SET domain-containing protein 8
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Pathway
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Disease
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Publication Reference
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PR-Set7 is a nucleosome-specific methyltransferase that modifies lysine 20 of histone H4 and is associated with silent chromatin.
Nishioka K, Rice JC, Sarma K, Erdjument-Bromage H, Werner J, Wang Y, Chuikov S, Valenzuela P, Tempst P, Steward R, Lis JT, Allis CD, Reinberg D.
Molecular Cell 2002 Jun; 9(6):1201.
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PR-Set7 is a nucleosome-specific methyltransferase that modifies lysine 20 of histone H4 and is associated with silent chromatin.
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