SNCA polyclonal antibody
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More Files
- More Functions
Western Blot
1. Cell lysate lacking SNCA 10,000 ng (negative control).
2. Human plasma 10,000 ng (negative control).
3. Human SNCA 100 ng.
4. Human SNCA 10 ng.
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Specifications
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of SNCA.
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to human SNCA.
Host
Rabbit
Reactivity
Human
Form
Lyophilized
Recommend Usage
Western Blot (1:1000)
ELISA (1:3000)
The optimal working dilution should be determined by the end user.Storage Buffer
Lyophilized from serum
Storage Instruction
Store at -20°C on dry atmosphere.
After reconstitution with sterile water, store at -20°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Western Blot
1. Cell lysate lacking SNCA 10,000 ng (negative control).
2. Human plasma 10,000 ng (negative control).
3. Human SNCA 100 ng.
4. Human SNCA 10 ng.Enzyme-linked Immunoabsorbent Assay
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Gene Info — SNCA
Entrez GeneID
6622Protein Accession#
P37840Gene Name
SNCA
Gene Alias
MGC110988, NACP, PARK1, PARK4, PD1
Gene Description
synuclein, alpha (non A4 component of amyloid precursor)
Gene Ontology
HyperlinkGene Summary
Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Four alternatively spliced transcripts encoding two different isoforms have been identified for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000161559|OTTHUMP00000161561|alpha synuclein|alpha-synuclein|alpha-synuclein, isoform NACP140|non A-beta component of AD amyloid|non A4 component of amyloid
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Interactomes
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Diseases
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