SNCA recombinant monoclonal antibody, clone 10E5
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More Files
- More Functions
Immunohistochemistry
Immunohistochemistry image of SNCA recombinant monoclonal antibody, clone 10E5 diluted at 1:100 and staining in paraffin-embedded human brain tissue performed on a Leica BondTM system.
Immunofluorescence
Immunofluorescence staining of SH-SY5Y Cells with SNCA recombinant monoclonal antibody, clone 10E5 at 1:300, counter-stained with DAPI.
Flow Cytometry
Overlay Peak curve showing SH-SY5Y cells stained with SNCA recombinant monoclonal antibody, clone 10E5 (red line) at 1:100.
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human SNCA.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against a synthetic peptide corresponding to human SNCA.
Reactivity
Human
Form
Liquid
Purification
Affinity chromatography purification
Isotype
IgG
Recommend Usage
ELISA
Flow Cytometry(1:50-1:200)
Immunohistochemistry(1:50-1:200)
Immunofluorescence(1:20-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH7.4 (150 mM NaCl, 0.02% sodium azide and 50% glycerol)
Storage Instruction
Store at -20°C or -80°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry
Immunohistochemistry image of SNCA recombinant monoclonal antibody, clone 10E5 diluted at 1:100 and staining in paraffin-embedded human brain tissue performed on a Leica BondTM system.Immunofluorescence
Immunofluorescence staining of SH-SY5Y Cells with SNCA recombinant monoclonal antibody, clone 10E5 at 1:300, counter-stained with DAPI.Enzyme-linked Immunoabsorbent Assay
Flow Cytometry
Overlay Peak curve showing SH-SY5Y cells stained with SNCA recombinant monoclonal antibody, clone 10E5 (red line) at 1:100. -
Gene Info — SNCA
Entrez GeneID
6622Protein Accession#
P37840Gene Name
SNCA
Gene Alias
MGC110988, NACP, PARK1, PARK4, PD1
Gene Description
synuclein, alpha (non A4 component of amyloid precursor)
Gene Ontology
HyperlinkGene Summary
Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Four alternatively spliced transcripts encoding two different isoforms have been identified for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000161559|OTTHUMP00000161561|alpha synuclein|alpha-synuclein|alpha-synuclein, isoform NACP140|non A-beta component of AD amyloid|non A4 component of amyloid
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Interactome
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Disease
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