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Last updated: 2017/2/19
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DAXX polyclonal antibody

  • Catalog # : PAB13554
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of DAXX.
  • Immunogen:
  • A synthetic peptide corresponding to amino acids 722-740 of human DAXX.
  • Host:
  • Rabbit
  • Reactivity:
  • Human, Mouse, Rat
  • Form:
  • Liquid
  • Recommend Usage:
  • Western Blot (1:500-1:1000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.02% sodium azide)
  • Storage Instruction:
  • Store at 4°C.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis of 50 ug of total cell lysate from HeLa cells with DAXX polyclonal antibody (Cat # PAB13554) at 1 : 1,000 dilution.
  • Immunohistochemistry
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Immunohistochemistry
  • Gene Information
  • Entrez GeneID:
  • 1616
  • Gene Name:
  • DAXX
  • Gene Alias:
  • BING2,DAP6,EAP1,MGC126245,MGC126246
  • Gene Description:
  • death-domain associated protein
  • Gene Summary:
  • This gene encodes a multifunctional protein that resides in multiple locations in the nucleus and in the cytoplasm. It interacts with a wide variety of proteins, such as apoptosis antigen Fas, centromere protein C, and transcription factor erythroblastosis virus E26 oncogene homolog 1. In the nucleus, the encoded protein functions as a potent transcription repressor that binds to sumoylated transcription factors. Its repression can be relieved by the sequestration of this protein into promyelocytic leukemia nuclear bodies or nucleoli. This protein also associates with centromeres in G2 phase. In the cytoplasm, the encoded protein may function to regulate apoptosis. The subcellular localization and function of this protein are modulated by post-translational modifications, including sumoylation, phosphorylation and polyubiquitination. Alternative splicing results in multiple transcript variants. [provided by RefSeq
  • Other Designations:
  • CENP-C binding protein,ETS1-associated protein 1,Fas-binding protein,OTTHUMP00000029289,OTTHUMP00000029290,death-associated protein 6
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