CCR3 polyclonal antibody
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
Western Blot (Tissue lysate)
Western blot analysis of CCR3 in human spleen tissue lysates with CCR3 polyclonal antibody (Cat # PAB13065) at 1 (lane 1) and 2 ug/mL (lane 2), and 2 ug/mL in the presence of blocking peptide (lane 3).
-
Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of CCR3.
Immunogen
A synthetic peptide corresponding to N-terminus 14 amino acids of human CCR3.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Form
Liquid
Recommend Usage
Western Blot (1-2 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Applications
Western Blot (Tissue lysate)
Western blot analysis of CCR3 in human spleen tissue lysates with CCR3 polyclonal antibody (Cat # PAB13065) at 1 (lane 1) and 2 ug/mL (lane 2), and 2 ug/mL in the presence of blocking peptide (lane 3). -
Gene Info — CCR3
Entrez GeneID
1232Protein Accession#
NP_847899Gene Name
CCR3
Gene Alias
CC-CKR-3, CD193, CKR3, CMKBR3, MGC102841
Gene Description
chemokine (C-C motif) receptor 3
Omim ID
601268Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a receptor for C-C type chemokines. It belongs to family 1 of the G protein-coupled receptors. This receptor binds and responds to a variety of chemokines, including eotaxin (CCL11), eotaxin-3 (CCL26), MCP-3 (CCL7), MCP-4 (CCL13), and RANTES (CCL5). It is highly expressed in eosinophils and basophils, and is also detected in TH1 and TH2 cells, as well as in airway epithelial cells. This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway. It is also known to be an entry co-receptor for HIV-1. This gene and seven other chemokine receptor genes form a chemokine receptor gene cluster on the chromosomal region 3p21. Alternatively spliced transcript variants have been described. [provided by RefSeq
Other Designations
CC chemokine receptor 3|OTTHUMP00000164718|b-chemokine receptor|eosinophil CC chemokine receptor 3|eosinophil eotaxin receptor
-
Interactome
-
Pathway
-
Disease
-
Publication Reference
-
Dynamic altruistic cooperation within breast tumors.
Muhammad Sufyan Bin Masroni, Kee Wah Lee, Victor Kwan Min Lee, Siok Bian Ng, Chao Teng Law, Kok Siong Poon, Bernett Teck-Kwong Lee, Zhehao Liu, Yuen Peng Tan, Wee Ling Chng, Steven Tucker, Lynette Su-Mien Ngo, George Wai Cheong Yip, Min En Nga, Susan Swee Shan Hue, Thomas Choudary Putti, Boon Huat Bay, Qingsong Lin, Lihan Zhou, Mikael Hartman, Tze Ping Loh, Manikandan Lakshmanan, Sook Yee Lee, Vinay Tergaonkar, Huiwen Chua, Adeline Voon Hui Lee, Eric Yew Meng Yeo, Mo-Huang Li, Chan Fong Chang, Z
Molecular cancer 2023 Dec; 22(1):206.
Application：N/A, N/A, N/A.
-
The beta-chemokine receptors CCR3 and CCR5 facilitate infection by primary HIV-1 isolates.
Choe H, Farzan M, Sun Y, Sullivan N, Rollins B, Ponath PD, Wu L, Mackay CR, LaRosa G, Newman W, Gerard N, Gerard C, Sodroski J.
Cell 1996 Jun; 85(7):1135.
-
Identification of a major co-receptor for primary isolates of HIV-1.
Deng H, Liu R, Ellmeier W, Choe S, Unutmaz D, Burkhart M, Di Marzio P, Marmon S, Sutton RE, Hill CM, Davis CB, Peiper SC, Schall TJ, Littman DR, Landau NR.
Nature 1996 Jun; 381(6584):661.
Application：WB-Tr, Mouse, NIH/3T3 cells.
-
HIV-1 entry cofactor: functional cDNA cloning of a seven-transmembrane, G protein-coupled receptor.
Feng Y, Broder CC, Kennedy PE, Berger EA.
Science 1996 May; 272(5263):872.
-
Dynamic altruistic cooperation within breast tumors.
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com