CCR3 recombinant monoclonal antibody, clone 5E8-G9-B4
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More Files
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Flow Cytometry
Flow cytometric analysis of human leukocytes with CCR3 recombinant monoclonal antibody, clone 5E8-G9-B4 (Cat # RAB03127).
Human leukocytes were stained with an isotype control (3.0- panel A) or the rmeric version of 5 RAB03127 (panel B) at a concentration of 1 ug/ml for 30 mins at RT. After washing- bound antibody was detected using a AF488 conjugated donkey anti-ribody and cells analysed on a FACSCanto flow-cytometer.
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human CCR3.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against recombinant protein corresponding to human CCR3.
Reactivity
Human
Form
Liquid
Isotype
IgG
Recommend Usage
Flow Cytometry
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS with 0.02% Proclin 300
Storage Instruction
Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Flow Cytometry
Flow cytometric analysis of human leukocytes with CCR3 recombinant monoclonal antibody, clone 5E8-G9-B4 (Cat # RAB03127).
Human leukocytes were stained with an isotype control (3.0- panel A) or the rmeric version of 5 RAB03127 (panel B) at a concentration of 1 ug/ml for 30 mins at RT. After washing- bound antibody was detected using a AF488 conjugated donkey anti-ribody and cells analysed on a FACSCanto flow-cytometer. -
Gene Info — CCR3
Entrez GeneID
1232Gene Name
CCR3
Gene Alias
CC-CKR-3, CD193, CKR3, CMKBR3, MGC102841
Gene Description
chemokine (C-C motif) receptor 3
Omim ID
601268Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a receptor for C-C type chemokines. It belongs to family 1 of the G protein-coupled receptors. This receptor binds and responds to a variety of chemokines, including eotaxin (CCL11), eotaxin-3 (CCL26), MCP-3 (CCL7), MCP-4 (CCL13), and RANTES (CCL5). It is highly expressed in eosinophils and basophils, and is also detected in TH1 and TH2 cells, as well as in airway epithelial cells. This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway. It is also known to be an entry co-receptor for HIV-1. This gene and seven other chemokine receptor genes form a chemokine receptor gene cluster on the chromosomal region 3p21. Alternatively spliced transcript variants have been described. [provided by RefSeq
Other Designations
CC chemokine receptor 3|OTTHUMP00000164718|b-chemokine receptor|eosinophil CC chemokine receptor 3|eosinophil eotaxin receptor
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Interactome
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