TICAM1 polyclonal antibody
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More Files
- More Functions
Western Blot (Tissue lysate)
Western blot analysis of TICAM1 in human lung tissue lysates with TICAM1 polyclonal antibody (Cat # PAB12905) at (A) 2 and (B) 4 ug/mL .
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry of TICAM1 in human lung tissue with TICAM1 polyclonal antibody (Cat # PAB12905) at 10 ug/mL .
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of TICAM1.
Immunogen
A synthetic peptide corresponding to C-terminus 14 amino acids of human TICAM1.
Host
Rabbit
Reactivity
Human
Form
Liquid
Recommend Usage
Western Blot (2-4 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of TICAM1 in human lung tissue lysates with TICAM1 polyclonal antibody (Cat # PAB12905) at (A) 2 and (B) 4 ug/mL .Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry of TICAM1 in human lung tissue with TICAM1 polyclonal antibody (Cat # PAB12905) at 10 ug/mL . -
Gene Info — TICAM1
Entrez GeneID
148022Protein Accession#
NP_891549Gene Name
TICAM1
Gene Alias
MGC35334, PRVTIRB, TICAM-1, TRIF
Gene Description
toll-like receptor adaptor molecule 1
Omim ID
607601Gene Ontology
HyperlinkGene Summary
TRIF, or TICAM1, is a Toll/IL1R (MIM 147810) (TIR) domain-containing adaptor molecule, like MYD88 (MIM 602170) and TIRAP (MIM 606252), that induces interferon-beta (IFNB; MIM 147640), specifically interacts with TLR3 (MIM 603029), and activates nuclear factor kappa-B (NFKB; see MIM 164011).[supplied by OMIM
Other Designations
TIR domain containing adaptor inducing interferon-beta|TIR domain-containing adaptor molecule 1
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Interactome
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Pathway
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Disease
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Publication Reference
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The Toll-IL-1 receptor adaptor family grows to five members.
O'Neill LA, Fitzgerald KA, Bowie AG.
Trends in Immunology 2003 Jun; 24(6):286.
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Toll-like receptors.
Takeda K, Kaisho T, Akira S.
Annual Review of Immunology 2001 Dec; 21:335.
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Innate immune recognition.
Janeway CA Jr, Medzhitov R.
Annual Review of Immunology 2001 Oct; 20:197.
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The Toll-IL-1 receptor adaptor family grows to five members.
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