TICAM1 polyclonal antibody
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human kidney with TICAM1 polyclonal antibody (Cat # PAB31491) shows strong cytoplasmic positivity in cells in tubules.
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Specification
Product Description
Rabbit polyclonal antibody raised against partial recombinant human TICAM1.
Immunogen
Recombinant protein corresponding to human TICAM1.
Sequence
AFDILGAAGQDKLLYLKHKLKTPRPGCQGQDLLHAMVLLKLGQETEARISLEALKADAVARLVARQWAGVDSTEDPEEPPDVSWAVARLYHL
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human kidney with TICAM1 polyclonal antibody (Cat # PAB31491) shows strong cytoplasmic positivity in cells in tubules. -
Gene Info — TICAM1
Entrez GeneID
148022Protein Accession#
Q8IUC6Gene Name
TICAM1
Gene Alias
MGC35334, PRVTIRB, TICAM-1, TRIF
Gene Description
toll-like receptor adaptor molecule 1
Omim ID
607601Gene Ontology
HyperlinkGene Summary
TRIF, or TICAM1, is a Toll/IL1R (MIM 147810) (TIR) domain-containing adaptor molecule, like MYD88 (MIM 602170) and TIRAP (MIM 606252), that induces interferon-beta (IFNB; MIM 147640), specifically interacts with TLR3 (MIM 603029), and activates nuclear factor kappa-B (NFKB; see MIM 164011).[supplied by OMIM
Other Designations
TIR domain containing adaptor inducing interferon-beta|TIR domain-containing adaptor molecule 1
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Interactome
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Pathway
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Disease
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