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Last updated: 2016/11/27
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NLRC4 polyclonal antibody

  • Catalog # : PAB12895
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of NLRC4.
  • Immunogen:
  • A synthetic peptide corresponding to C-terminus of human NLRC4.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Specificity:
  • A 110 KDa band can be detected. Ipaf antibody is human specific.
  • Form:
  • Liquid
  • Recommend Usage:
  • Western Blot (0.5-2 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.02% sodium azide)
  • Storage Instruction:
  • Store at 4°C for three months. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis of NLRC4 in human PBL lysate with NLRC4 polyclonal antibody (Cat # PAB12895) at 0.5 (lane A), 1 (lane B), and 2 (lane C) ug/mL , respectively.
  • Immunocytochemistry
  • Immunocytochemistry
  • Immunocytochemistry of NLRC4 in THP-1 cells with NLRC4 polyclonal antibody (Cat # PAB12895) at 10 ug/mL .
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Gene Information
  • Gene Name:
  • NLRC4
  • Gene Alias:
  • CARD12,CLAN,CLAN1,CLANA,CLANB,CLANC,CLAND,CLR2.1,IPAF
  • Gene Description:
  • NLR family, CARD domain containing 4
  • Gene Summary:
  • In C. elegans, Ced4 binds and activates Ced3, an apoptotic initiator caspase, via caspase-associated recruitment domains (CARDs). Human Ced4 homologs include APAF1 (MIM 602233), NOD1/CARD4 (MIM 605980), and NOD2/CARD15 (MIM 605956). These proteins have at least 1 N-terminal CARD domain followed by a centrally located nucleotide-binding domain (NBD or NACHT) and a C-terminal regulatory domain, found only in mammals, that contains either WD40 repeats or leucine-rich repeats (LRRs). CARD12 is a member of the Ced4 family and can induce apoptosis.[supplied by OMIM
  • Other Designations:
  • ICE-protease activating factor,NOD-like receptor C4,caspase recruitment domain family, member 12,caspase recruitment domain protein 12,nucleotide-binding oligomerization domain, leucine rich repeat and CARD domain containing 4
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