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Last updated: 2017/10/15

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DOK1 polyclonal antibody

  • Catalog # : PAB12821
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of DOK1.
  • Immunogen:
  • A synthetic peptide corresponding to C-terminus of human DOK1.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Specificity:
  • A 62 KDa band should be detected.
  • Form:
  • Liquid
  • Recommend Usage:
  • Western Blot (0.5-1 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.02% sodium azide)
  • Storage Instruction:
  • Store at 4°C for three months. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis of DOK1 in Jurkat (Jur) and THP-1 (THP) cell lysates with DOK1 polyclonal antibody (Cat # PAB12821) at 1 ug/mL .
  • Immunocytochemistry
  • Immunocytochemistry
  • Immunocytochemistry of DOK1 in K-562 cells with DOK1 polyclonal antibody (Cat # PAB12821) at 2 ug/mL .
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 1796
  • Gene Name:
  • DOK1
  • Gene Alias:
  • MGC117395,MGC138860,P62DOK
  • Gene Description:
  • docking protein 1, 62kDa (downstream of tyrosine kinase 1)
  • Gene Summary:
  • Docking protein 1 is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. Docking protein 1 contains a putative pleckstrin homology domain at the amino terminus and ten PXXP SH3 recognition motifs. Docking protein 2 binds p120 (RasGAP) from CML cells. It has been postulated to play a role in mitogenic signaling. [provided by RefSeq
  • Other Designations:
  • Downstream of tyrosine kinase 1,docking protein 1,docking protein 1 (downstream of tyrosine kinase 1),docking protein 1, 62kD (downstream of tyrosine kinase 1)
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