DLL1 polyclonal antibody
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More Files
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Western Blot (Tissue lysate)
DLL1 polyclonal antibody (Cat # PAB12816) (0.3 ug/mL) staining of rat heart lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of DLL1.
Immunogen
A synthetic peptide corresponding to amino acids at internal region of human DLL1.
Sequence
C-ATQRHLTVGEEWSQD
Host
Goat
Theoretical MW (kDa)
78
Reactivity
Mouse, Rat
Specificity
75 KDa band observed in Mouse Heart and Rat Heart lysates (calculated MW of 78.1 KDa according to human NP_005609.3, 78.5K Da according to Mouse NP_031891.2 and 77.4 KDa according to Rat NP_114452.1). Recommended concentration: 0.3-1 ug/ml.
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Recommend Usage
ELISA (1:16000)
Western blot (0.3-1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
DLL1 polyclonal antibody (Cat # PAB12816) (0.3 ug/mL) staining of rat heart lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.Enzyme-linked Immunoabsorbent Assay
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Gene Info — DLL1
Entrez GeneID
28514Protein Accession#
NP_005609.3Gene Name
DLL1
Gene Alias
DELTA1, DL1, Delta
Gene Description
delta-like 1 (Drosophila)
Omim ID
606582Gene Ontology
HyperlinkGene Summary
DLL1 is a human homolog of the Notch Delta ligand and is a member of the delta/serrate/jagged family. It plays a role in mediating cell fate decisions during hematopoiesis. It may play a role in cell-to-cell communication. [provided by RefSeq
Other Designations
OTTHUMP00000017690|delta-like 1|delta-like 1 protein
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Interactome
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Pathway
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Disease
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Publication Reference
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Decreased Satellite Cell Number and Function in Humans and Mice With Type 1 Diabetes Mellitus is the Result of Altered Notch Signaling.
D'Souza DM, Zhou S, Rebalka IA, MacDonald B, Moradi J, Krause MP, Al-Sajee D, Punthakee Z, Tarnopolsky MA, Hawke TJ.
Diabetes 2016 Jun; 65(10):3053.
Application：WB-Ti, Mouse, Whole muscle skeletal muscle lysate.
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MicroRNA regulation of cell lineages in mouse and human embryonic stem cells.
Ivey KN, Muth A, Arnold J, King FW, Yeh RF, Fish JE, Hsiao EC, Schwartz RJ, Conklin BR, Bernstein HS, Srivastava D.
Cell Stem Cell 2008 Mar; 2(3):219.
Application：IF, Mouse, Mouse embryonic stem cells.
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Decreased Satellite Cell Number and Function in Humans and Mice With Type 1 Diabetes Mellitus is the Result of Altered Notch Signaling.
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