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Last updated: 2016/12/4
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SOCS2 polyclonal antibody

  • Catalog # : PAB12779
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of SOCS2.
  • Immunogen:
  • A synthetic peptide corresponding to C-terminus of human, mouse and rat SOCS2.
  • Host:
  • Rabbit
  • Theoretical MW (kDa):
  • 23
  • Reactivity:
  • Human, Mouse
  • Specificity:
  • This antibody recognizes ~23 KDa of SOCS2.
  • Form:
  • Liquid
  • Quality Control Testing:
  • Antibody Reactive Against Synthetic Peptide.
  • Recommend Usage:
  • Western Blot (0.1-1 ug/mL)
    ELISA (0.01-0.1 ug/mL)
    Immunoprecipitation (2-5 ug/mL)
    Immunohistochemistry (0.5-2 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In TBS, pH 7.2 (BSA, 10% Proclin300)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C or lower.
    Aliquot to avoid repeated freezing and thawing.
  • Publication Reference
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • The tissue lysates derived from mouse liver (Lane 1), mouse muscle (Lane 2) were immunoprobed by SOCS2 polyclonal antibody (Cat # PAB12779) at 1 : 500. An immunoreactive band is observed around ~23kDa.
  • Immunohistochemistry
  • Immunoprecipitation
  • ELISA
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • Immunohistochemistry
  • Immunoprecipitation
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 8835
  • Gene Name:
  • SOCS2
  • Gene Alias:
  • CIS2,Cish2,SOCS-2,SSI-2,SSI2,STATI2
  • Gene Description:
  • suppressor of cytokine signaling 2
  • Gene Summary:
  • This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including erythropoietin, GM-CSF, IL10 and interferon (IFN)-gamma. The protein encoded by this gene is found to interact with the cytoplasmic domain of insulin-like growth factor-1 receptor (IGF1R), and thus is thought to be involved in the regulation of IGF1R mediated cell signaling. Knockout studies in mice also suggested a regulatory role of this gene in IGF-1 related growth control. [provided by RefSeq
  • Other Designations:
  • STAT induced STAT inhibitor-2,cytokine-inducible SH2 protein 2,suppressor of cytokine signaling-2
  • Gene Information
  • Gene Name:
  • Socs2
  • Gene Alias:
  • 8030460M17,AI527257,AW108012,CIS2,Cish2,D130043N08Rik,JAB,MGC118106,SOCS-2,SSI-2,hg
  • Gene Description:
  • suppressor of cytokine signaling 2
  • Other Designations:
  • STAT-induced STAT inhibitor 2,cytokine inducible SH2-containing protein 2,cytokine-inducible SH2 protein 2
  • Gene Information
  • Gene Name:
  • Socs2
  • Gene Alias:
  • Cish2,Socs-2
  • Gene Description:
  • suppressor of cytokine signaling 2
  • Other Designations:
  • cytokine inducible SH2-containing protein 2
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