SOCS2 recombinant monoclonal antibody, clone R03-4D9
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More Files
- More Functions
Western Blot
Western blot analysis of K562 lysates with SOCS2 recombinant monoclonal antibody, clone R03-4D9 (Cat # RAB01903).
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human SOCS2.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against a synthetic peptide corresponding to human SOCS2.
Theoretical MW (kDa)
Calculated MW: 22 kD
Reactivity
Human
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Immunoprecipitation (1:20)
Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In 50 mM Tris-Glycine, pH 7.4 (0.15 M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA)
Storage Instruction
Store at -20 °C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western blot analysis of K562 lysates with SOCS2 recombinant monoclonal antibody, clone R03-4D9 (Cat # RAB01903).Immunoprecipitation
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Gene Info — SOCS2
Entrez GeneID
8835Protein Accession#
O14508Gene Name
SOCS2
Gene Alias
CIS2, Cish2, SOCS-2, SSI-2, SSI2, STATI2
Gene Description
suppressor of cytokine signaling 2
Omim ID
605117Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including erythropoietin, GM-CSF, IL10 and interferon (IFN)-gamma. The protein encoded by this gene is found to interact with the cytoplasmic domain of insulin-like growth factor-1 receptor (IGF1R), and thus is thought to be involved in the regulation of IGF1R mediated cell signaling. Knockout studies in mice also suggested a regulatory role of this gene in IGF-1 related growth control. [provided by RefSeq
Other Designations
STAT induced STAT inhibitor-2|cytokine-inducible SH2 protein 2|suppressor of cytokine signaling-2
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Interactome
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Pathway
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Disease
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