SOX9 polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
The whole cell lysate derived from LNCaP was immunoblotted by SOX9 polyclonal antibody (Cat # PAB12736) at 1 : 500 (Lane 1), Lane 2 is a negative control.
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of SOX9.
Immunogen
A synthetic peptide corresponding to internal domain of human SOX9.
Host
Rabbit
Theoretical MW (kDa)
56
Reactivity
Human, Mouse, Rat
Specificity
This antibody recognizes ~56 KDa of human SOX9.
Form
Liquid
Recommend Usage
ELISA (0.01-0.1 ug/mL)
Immunohistochemistry (2-5 ug/mL)
Immunoprecipitation (2-5 ug/mL)
Western Blot (0.1-1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (Antibody stabilizer).
Storage Instruction
Store at 4°C for three month without detectable loss of activity. For long term storage, store at -20°C to -80°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Western Blot (Cell lysate)
The whole cell lysate derived from LNCaP was immunoblotted by SOX9 polyclonal antibody (Cat # PAB12736) at 1 : 500 (Lane 1), Lane 2 is a negative control.Immunohistochemistry
Immunoprecipitation
Enzyme-linked Immunoabsorbent Assay
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Gene Info — SOX9
Entrez GeneID
6662Gene Name
SOX9
Gene Alias
CMD1, CMPD1, SRA1
Gene Description
SRY (sex determining region Y)-box 9
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene recognizes the sequence CCTTGAG along with other members of the HMG-box class DNA-binding proteins. It acts during chondrocyte differentiation and, with steroidogenic factor 1, regulates transcription of the anti-Muellerian hormone (AMH) gene. Deficiencies lead to the skeletal malformation syndrome campomelic dysplasia, frequently with sex reversal. [provided by RefSeq
Other Designations
SRY (sex determining region Y)-box 9 (campomelic dysplasia, autosomal sex-reversal)|SRY (sex-determining region Y)-box 9 (campomelic dysplasia, autosomal sex-reversal)|SRY (sex-determining region Y)-box 9 protein|campomelic dysplasia, autosomal sex-revers
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Interactome
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Disease
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Publication Reference
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The role of Sox9 in mouse mammary gland development and maintenance of mammary stem and luminal progenitor cells.
Malhotra GK, Zhao X, Edwards E, Kopp JL, Naramura M, Sander M, Band H, Band V.
BMC Developmental Biology 2014 Dec; 14(1):47.
Application：WB-Ce, Human, Mammary stem/progenitor, Myoepithelial cells.
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Prostaglandin E2 supports growth of chicken embryo intestinal organoids in Matrigel matrix.
Pierzchalska M, Grabacka M, Michalik M, Zyla K, Pierzchalski P.
Biotechniques 2012 May; 52(5):307.
Application：IP, Chicken, Epithelial tissue was obtained from embryonic chicken intestine.
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SOX9 is expressed in normal prostate basal cells and regulates androgen receptor expression in prostate cancer cells.
Wang H, McKnight NC, Zhang T, Lu ML, Balk SP, Yuan X.
Cancer Research 2007 Jan; 67(2):528.
Application：IHC-P, WB, Human, C3H10T, CWR22Rv1, RCS cells, Human prostate cancer.
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The role of Sox9 in mouse mammary gland development and maintenance of mammary stem and luminal progenitor cells.
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