NUP53 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against recombinant NUP53.
Immunogen
Recombinant protein corresponding to Yeast NUP53.
Host
Rabbit
Reactivity
Yeast
Specificity
Yeast Nup53p.
Form
Liquid
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Recommend Usage
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In antiserum (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot of Nup53p polyclonal antibody (Cat # PAB12343) on yeast preparation.Immunofluorescence
Immunofluorescence showing Nup53p polyclonal antibody (Cat # PAB12343) on yeast. -
Gene Info — NUP53
Entrez GeneID
855184Gene Name
NUP53
Gene Alias
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Gene Description
Nup53p
Gene Ontology
HyperlinkGene Summary
interacts with karyopherin Kap121p or with Nup170p via overlapping regions of Nup53p
Other Designations
Subunit of the nuclear pore complex (NPC), interacts with karyopherin Kap121p or with Nup170p via overlapping regions of Nup53p, involved in activation of the spindle checkpoint mediated by the Mad1p-Mad2p complex
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Publication Reference
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Vertebrate Nup53 interacts with the nuclear lamina and is required for the assembly of a Nup93-containing complex.
Hawryluk-Gara LA, Shibuya EK, Wozniak RW.
Molecular Biology of the Cell 2005 Feb; 16(5):2382.
Application:IF, WB, Human, Rat, HeLa cells, Rat livers.
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Vertebrate Nup53 interacts with the nuclear lamina and is required for the assembly of a Nup93-containing complex.
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