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Last updated: 2017/1/15
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CUL4B polyclonal antibody

  • Catalog # : PAB12320
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of CUL4B.
  • Immunogen:
  • A synthetic peptide corresponding to human CUL4B.
  • Host:
  • Rabbit
  • Theoretical MW (kDa):
  • 76.8, 87.6
  • Reactivity:
  • Human, Rat, Zebra fish
  • Specificity:
  • Identical to the related rat and mouse sequence.
  • Form:
  • Lyophilized
  • Purification:
  • Affinity purification
  • Isotype:
  • IgG
  • Recommend Usage:
  • Western Blot (1 ug/mL)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (2 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • Lyophilized from 0.9 mg NaCl, 0.2 mg Na2HPO4 (5 mg BSA, 0.05 mg sodium azide, 0.05 mg Thimerosal)
  • Storage Instruction:
  • Store at -20°C on dry atmosphere.
    After reconstitution with 200 uL of deionized water and concentration will be 500 ug/mL, store at -20°C or lower.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide and thimerosal: POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot
  • Western Blot
  • Western Blot analysis of CUL4B expression from cell and tissue extracts with CUL4B polyclonal antibody (Cat # PAB12320).
    Lane 1 : female zebrafish tissue lysate.
    Lane 2 : MM453 whole cell lysate.
    Lane 3 : rat liver tissue lysate.
    Lane 4 : rat lung tissue lysate.
    Lane 5 : MCF-7 whole cell lysate.
    Lane 6 : MM231 whole cell lysate.
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical staining of CUL4B on formalin fixed, paraffin embedded zebrafish body with CUL4B polyclonal antibody (Cat # PAB12320).
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 8450
  • Gene Name:
  • CUL4B
  • Gene Alias:
  • DKFZp686F1470,KIAA0695,MRXHF2,MRXSC,SFM2
  • Gene Description:
  • cullin 4B
  • Gene Summary:
  • This gene is a member of the cullin family. The encoded protein forms a complex that functions as an E3 ubiquitin ligase and catalyzes the polyubiquitination of specific protein substrates in the cell. The protein interacts with a ring finger protein, and is required for the proteolysis of several regulators of DNA replication including chromatin licensing and DNA replication factor 1 and cyclin E. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000023946,OTTHUMP00000023947,cullin-4B
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