Rabbit polyclonal antibody raised against synthetic peptide of LMNB1.
A synthetic peptide corresponding to amino acids at C-terminus of human LMNB1.
Human, Mouse, Rat
Different from the related rat and mouse sequence by three amino acids.
Western Blot (1-2 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.5-1 ug/mL) Immunohistochemistry (Frozen sections) (0.5-1 ug/mL) Immunocytochemistry (0.5-1 ug/mL) The optimal working dilution should be determined by the end user.
The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B1. [provided by RefSeq