LMNB1 monoclonal antibody, clone CL3929
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human tonsil shows strong nuclear membrane immunoreactivity in lymphoid cells.
Immunofluorescence
Immunofluorescence staining of U-251 cell with antibody shows specific staining of nuclear membrane in green. Microtubule-and nuclear probes are visualized in red and blue, respectively.
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Specification
Product Description
Mouse monoclonal antibody raised against synthetic peptide of human LMNB1.
Immunogen
A synthetic peptide corresponding to human LMNB1.
Sequence
RTTRGKRKRVDVEESEASSSVSISHSASA
Host
Mouse
Reactivity
Human
Form
Liquid
Purification
Protein A purification
Isotype
IgG1
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:500-1:1000)
Immunofluorescence (1-4 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human tonsil shows strong nuclear membrane immunoreactivity in lymphoid cells.Immunofluorescence
Immunofluorescence staining of U-251 cell with antibody shows specific staining of nuclear membrane in green. Microtubule-and nuclear probes are visualized in red and blue, respectively. -
Gene Info — LMNB1
Entrez GeneID
4001Protein Accession#
P20700Gene Name
LMNB1
Gene Alias
ADLD, LMN, LMN2, LMNB, MGC111419
Gene Description
lamin B1
Gene Ontology
HyperlinkGene Summary
The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B1. [provided by RefSeq
Other Designations
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Interactome
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Disease
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