PODXL polyclonal antibody
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More Files
- More Functions
Western Blot (Tissue lysate)
Western blot analysis of PODXL in human lung lysate using with PODXL polyclonal antibody (Cat # PAB12067).
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of PODXL.
Immunogen
A synthetic peptide corresponding to amino acids 100-200 of human PODXL.
Host
Rabbit
Reactivity
Human
Form
Liquid
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
Flow Cytometry (1:100)
Western Blot (2 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris-glycine, 150 mM NaCl (0.05% sodium azide)
Storage Instruction
Store at -20°C or -80°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of PODXL in human lung lysate using with PODXL polyclonal antibody (Cat # PAB12067).Flow Cytometry
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Gene Info — PODXL
Entrez GeneID
5420Protein Accession#
O00592Gene Name
PODXL
Gene Alias
Gp200, MGC138240, PC, PCLP
Gene Description
podocalyxin-like
Omim ID
602632Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the sialomucin protein family. The encoded protein was originally identified as an important component of glomerular podocytes. Podocytes are highly differentiated epithelial cells with interdigitating foot processes covering the outer aspect of the glomerular basement membrane. Other biological activities of the encoded protein include: binding in a membrane protein complex with Na+/H+ exchanger regulatory factor to intracellular cytoskeletal elements, playing a role in hematopoetic cell differentiation, and being expressed in vascular endothelium cells and binding to L-selectin. [provided by RefSeq
Other Designations
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Interactome
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Disease
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Publication Reference
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Podocalyxin variants and risk of prostate cancer and tumor aggressiveness.
Casey G, Neville PJ, Liu X, Plummer SJ, Cicek MS, Krumroy LM, Curran AP, McGreevy MR, Catalona WJ, Klein EA, Witte JS.
Human Molecular Genetics 2006 Mar; 15(5):735.
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Podocalyxin: a marker of blasts in acute leukemia.
Kelley TW, Huntsman D, McNagny KM, Roskelley CD, Hsi ED.
American Journal of Clinical Pathology 2005 Jul; 124(1):134.
Application：IHC-P, Human, Human acute myeloid leukemia.
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Overexpression of the anti-adhesin podocalyxin is an independent predictor of breast cancer progression.
Somasiri A, Nielsen JS, Makretsov N, McCoy ML, Prentice L, Gilks CB, Chia SK, Gelmon KA, Kershaw DB, Huntsman DG, McNagny KM, Roskelley CD.
Cancer Research 2004 Aug; 64(15):5068.
Application：IF, IHC-P, WB, Human, Human invasive breast tumors, MCF-7 cells.
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Podocalyxin variants and risk of prostate cancer and tumor aggressiveness.
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