GRIK3 polyclonal antibody
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More Files
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Western Blot (Tissue lysate)
GRIK3 polyclonal antibody (Cat # PAB11539) staining of rat brain lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of GRIK3.
Immunogen
A synthetic peptide corresponding to human GRIK3.
Sequence
C-KIRQLPIDSDDSRP
Host
Goat
Theoretical MW (kDa)
104
Reactivity
Mouse, Rat
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:64000)
Western Blot (0.3-1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
GRIK3 polyclonal antibody (Cat # PAB11539) staining of rat brain lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.Enzyme-linked Immunoabsorbent Assay
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Gene Info — GRIK3
Entrez GeneID
2899Protein Accession#
NP_000822.2Gene Name
GRIK3
Gene Alias
EAA5, GLR7, GLUR7, GluR7a
Gene Description
glutamate receptor, ionotropic, kainate 3
Omim ID
138243Gene Ontology
HyperlinkGene Summary
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. It is not certain if the subunit encoded by this gene is subject to RNA editing as the other 2 family members (GRIK1 and GRIK2). A Ser310Ala polymorphism has been associated with schizophrenia, and there are conflicting reports of its association with the pathogenesis of delirium tremens in alcoholics. [provided by RefSeq
Other Designations
OTTHUMP00000004360|dJ1090M5.1 (glutamate receptor, ionotropic, kainate 3 (GLUR7))|excitatory amino acid receptor 5|glutamate receptor 7
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Interactome
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Pathway
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Disease
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Publication Reference
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Chromosomal localization of gene for human glutamate receptor subunit-7.
Puranam RS, Eubanks JH, Heinemann SF, McNamara JO.
Somatic Cell and Molecular Genetics 1993 Nov; 19(6):581.
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Chromosomal localization of gene for human glutamate receptor subunit-7.
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