GRIK3 monoclonal antibody, clone 2B4H1
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Specification
Product Description
Mouse monoclonal antibody raised against recombinant human GRIK3.
Immunogen
Recombinant protein corresponding to amino acid 32-173 of human GRIK3 from E. coli.
Host
Mouse
Theoretical MW (kDa)
104
Reactivity
Human
Form
Liquid
Isotype
IgG1
Recommend Usage
ELISA (1:10000)
Western Blot (1:500-1:2000)
Immunocytochemistry
Flow Cytometry (1:200-1:400)
Immunohistochemistry
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.05% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of (1) A431 cell, (2) Hela cell with GRIK3 monoclonal antibody.Western Blot (Transfected lysate)
Western blot analysis of (1) HEK293 cells, (2) GRIK3-hIgGFc transfected HEK293 cell lysate.Enzyme-linked Immunoabsorbent Assay
ELISA analysis of GRIK3 monoclonal antibody, clone 2B4H1.Flow Cytometry
Flow cytometric analysis of Hela cells with GRIK3 monoclonal antibody (green) and negative control (red). -
Gene Info — GRIK3
Entrez GeneID
2899Gene Name
GRIK3
Gene Alias
EAA5, GLR7, GLUR7, GluR7a
Gene Description
glutamate receptor, ionotropic, kainate 3
Omim ID
138243Gene Ontology
HyperlinkGene Summary
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. It is not certain if the subunit encoded by this gene is subject to RNA editing as the other 2 family members (GRIK1 and GRIK2). A Ser310Ala polymorphism has been associated with schizophrenia, and there are conflicting reports of its association with the pathogenesis of delirium tremens in alcoholics. [provided by RefSeq
Other Designations
OTTHUMP00000004360|dJ1090M5.1 (glutamate receptor, ionotropic, kainate 3 (GLUR7))|excitatory amino acid receptor 5|glutamate receptor 7
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