Western blot using RAB11FIP3 polyclonal antibody (Cat # PAB11253) to detect RAB11FIP3 (arrowhead) in NIH/3T3 cells (lane 1), HeLa cells (lane 2) and 293T cells (lane 3). The primary antibody at a 1 : 2,000 dilution. Personal Communication, P. Randazzo, CCR-NCI, Bethesda, MD.
Proteins of the large Rab GTPase family (see RAB1A; MIM 179508) have regulatory roles in the formation, targeting, and fusion of intracellular transport vesicles. RAB11FIP3 is one of many proteins that interact with and regulate Rab GTPases (Hales et al., 2001 [PubMed 11495908]).[supplied by OMIM
PAC196A12.1,eferin,rab11-family interacting protein 3