SUPT16H polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against partial recombinant SUPT16H.
Immunogen
Recombinant GST fusion protein corresponding to amino acids 1-329 of human SUPT16H.
Host
Rabbit
Reactivity
Human, Mouse
Form
Liquid
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Recommend Usage
Western blot (5 to 10 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.08% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Immunoprecipitation
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Gene Info — SUPT16H
Entrez GeneID
11198Gene Name
SUPT16H
Gene Alias
CDC68, FACT, FACTP140, FLJ10857, FLJ14010, FLJ34357, SPT16/CDC68
Gene Description
suppressor of Ty 16 homolog (S. cerevisiae)
Omim ID
605012Gene Ontology
HyperlinkGene Summary
Transcription of protein-coding genes can be reconstituted on naked DNA with only the general transcription factors and RNA polymerase II. However, this minimal system cannot transcribe DNA packaged into chromatin, indicating that accessory factors may facilitate access to DNA. One such factor, FACT (facilitates chromatin transcription), interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT is composed of an 80 kDa subunit and a 140 kDa subunit; this gene encodes the 140 kDa subunit. [provided by RefSeq
Other Designations
chromatin-specific transcription elongation factor large subunit|facilitates chromatin remodeling 140 kDa subunit
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Interactome
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Publication Reference
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A DNA damage-induced p53 serine 392 kinase complex contains CK2, hSpt16, and SSRP1.
Keller DM, Zeng X, Wang Y, Zhang QH, Kapoor M, Shu H, Goodman R, Lozano G, Zhao Y, Lu H.
Molecular Cell 2001 Feb; 7(2):283.
Application：WB-Ce, Human, HeLa cells.
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A DNA damage-induced p53 serine 392 kinase complex contains CK2, hSpt16, and SSRP1.
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