S1PR4 polyclonal antibody
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More Files
- More Functions
Western Blot (Transfected lysate)
Western blot analysis using S1PR4 polyclonal antibody (Cat # PAB10364) on McA-RH7777 cells transfected with S1PR4 protein in the presence (lane 1) and absence (lane 2) of specific blocking peptide.
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of S1PR4.
Immunogen
A synthetic peptide corresponding to C-terminus of S1PR4.
Host
Rabbit
Reactivity
Human
Form
Liquid
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
Western blot (5 to 10 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.08% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
Western blot analysis using S1PR4 polyclonal antibody (Cat # PAB10364) on McA-RH7777 cells transfected with S1PR4 protein in the presence (lane 1) and absence (lane 2) of specific blocking peptide. -
Gene Info — S1PR4
Entrez GeneID
8698Gene Name
S1PR4
Gene Alias
EDG6, LPC1, S1P4, SLP4
Gene Description
sphingosine-1-phosphate receptor 4
Omim ID
603751Gene Ontology
HyperlinkGene Summary
This gene is a member of the endothelial differentiation, G-protein-coupled (EDG)) receptor gene family. EDG receptors bind lysophospholipids or lysosphingolipids as ligands, and are involved in cell signalling in many different cell types. This EDG receptor gene is intronless and is specifically expressed in the lymphoid tissue. [provided by RefSeq
Other Designations
Sphingosine 1-phosphate receptor 4|Sphingosine 1-phosphate receptor Edg-6|endothelial differentiation, G protein coupled receptor 6|endothelial differentiation, G-protein-coupled receptor 6|endothelial differentiation, lysophosphatidic acid G-protein-coup
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Interactome
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Pathway
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Publication Reference
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Subtype-specific, differential activities of the EDG family receptors for sphingosine-1-phosphate, a novel lysophospholipid mediator.
Takuwa Y, Okamoto H, Takuwa N, Gonda K, Sugimoto N, Sakurada S.
Molecular and Cellular Endocrinology 2001 May; 177(1-2):3.
Application：IHC, WB, Human, Lymphoid tissues.
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Sphingosine-1-phosphate is a ligand for the G protein-coupled receptor EDG-6.
Van Brocklyn JR, Graler MH, Bernhardt G, Hobson JP, Lipp M, Spiegel S.
Blood 2000 Apr; 95(8):2624.
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Edg-6 as a putative sphingosine 1-phosphate receptor coupling to Ca(2+) signaling pathway.
Yamazaki Y, Kon J, Sato K, Tomura H, Sato M, Yoneya T, Okazaki H, Okajima F, Ohta H.
Biochemical and Biophysical Research Communications 2000 Feb; 268(2):583.
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Subtype-specific, differential activities of the EDG family receptors for sphingosine-1-phosphate, a novel lysophospholipid mediator.
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