FGF2 polyclonal antibody
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Specification
Product Description
Sheep polyclonal antibody raised against full length recombinant FGF2.
Immunogen
Recombinant protein corresponding to full length human FGF2.
Host
Sheep
Reactivity
Human, Mouse, Rat
Specificity
A high level of specificity for bFGF was shown by immunohistochemistry for this antiserum.
Form
Lyophilized
Recommend Usage
Immunohistochemistry (1:1000-1:2000)
Western Blot (1:1000-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
Lyophilized from PBS
Storage Instruction
Store at 4°C on dry atmosphere.
After reconstitution with deionized water, store at -20°C or lower.
Aliquot to avoid repeated freezing and thawing. -
Applications
Western Blot
Immunohistochemistry (Frozen sections)
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Gene Info — FGF2
Entrez GeneID
2247Protein Accession#
P09038Gene Name
FGF2
Gene Alias
BFGF, FGFB, HBGF-2
Gene Description
fibroblast growth factor 2 (basic)
Omim ID
134920Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. This protein has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. The mRNA for this gene contains multiple polyadenylation sites, and is alternatively translated from non-AUG (CUG) and AUG initiation codons, resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF. [provided by RefSeq
Other Designations
basic fibroblast growth factor bFGF|fibroblast growth factor 2|heparin-binding growth factor 2|prostatropin
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Interactome
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Pathway
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Disease
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Publication Reference
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Critical Role of IP-10 on Reducing Experimental Corneal Neovascularization.
Liu G, Zhang W, Xiao Y, Lu P.
Current Eye Research 2015 Sep; 40(9):891.
Application:WB-Ti, Mouse, Corneas.
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Critical Role of IP-10 on Reducing Experimental Corneal Neovascularization.
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