FGF2 monoclonal antibody, clone AOHC-6
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Specification
Product Description
Rabbit monoclonal antibody raised against synthetic peptide of human FGF2.
Immunogen
A synthetic peptide corresponding to human FGF2.
Host
Rabbit
Theoretical MW (kDa)
30.77
Reactivity
Human
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Flow Cytometry (1:50)
Immunoprecipitation (1:50)
Western Blot (1:500-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide).
Storage Instruction
Store at -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western Blot analysis of K562 cell lysate with FGF2 monoclonal antibody, clone AOHC-6 (Cat # MAB20036).Immunoprecipitation
Flow Cytometry
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Gene Info — FGF2
Entrez GeneID
2247Protein Accession#
P09038Gene Name
FGF2
Gene Alias
BFGF, FGFB, HBGF-2
Gene Description
fibroblast growth factor 2 (basic)
Omim ID
134920Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. This protein has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. The mRNA for this gene contains multiple polyadenylation sites, and is alternatively translated from non-AUG (CUG) and AUG initiation codons, resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF. [provided by RefSeq
Other Designations
basic fibroblast growth factor bFGF|fibroblast growth factor 2|heparin-binding growth factor 2|prostatropin
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Interactome
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Pathway
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Disease
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