SOD1 polyclonal antibody
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More Files
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Western Blot
Western blot detection of human SOD1 using rabbit SOD1 polyclonal antibody (Cat # PAB0724) at a dilution of 1 in 500. This antibody detects a band of 16 KDa in human Jurkat T cell extracts (lane 2) . Its specificity for human SOD1 is shown by the lack of reactivity with mouse brain tissue extracts (lane 1) .
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of SOD1.
Immunogen
A synthetic peptide (conjugated diphtheria toxoid) corresponding to amino acids 24-36 of human SOD1.
Sequence
ESNGPVKVWGSIK
Host
Rabbit
Reactivity
Human
Form
Lyophilized
Recommend Usage
Western Blot (1:500-1:1000)
The optimal dilution should be determined by the end user.Storage Buffer
Lyophilized from PBS
Storage Instruction
Store at 4°C on dry atmosphere.
After reconstitution with deionized water, store at -20°C or lower.
Aliquot to avoid repeated freezing and thawing. -
Applications
Western Blot
Western blot detection of human SOD1 using rabbit SOD1 polyclonal antibody (Cat # PAB0724) at a dilution of 1 in 500. This antibody detects a band of 16 KDa in human Jurkat T cell extracts (lane 2) . Its specificity for human SOD1 is shown by the lack of reactivity with mouse brain tissue extracts (lane 1) . -
Gene Info — SOD1
Entrez GeneID
6647Protein Accession#
P00441Gene Name
SOD1
Gene Alias
ALS, ALS1, IPOA, SOD, homodimer
Gene Description
superoxide dismutase 1, soluble
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene. [provided by RefSeq
Other Designations
Cu /Zn superoxide dismutase|Cu/Zn superoxide dismutase|SOD, soluble|indophenoloxidase A|superoxide dismutase, cystolic
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Interactome
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Pathway
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Disease
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