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Last updated: 2016/11/27
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BAG3 polyclonal antibody

  • Catalog # : PAB0330
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against partial recombinant BAG3.
  • Immunogen:
  • Recombinant protein corresponding to C-terminus 196 amino acids of human BAG3.
  • Host:
  • Rabbit
  • Reactivity:
  • Human, Mouse
  • Form:
  • Liquid
  • Recommend Usage:
  • The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In serum (0.05% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • Western blot analysis of BAG3. Using BAG3 polyclonal antibody (Cat # PAB0330) at 1 : 2000. Tissue lysates, normalized for total protein (20 ug/lane) , were from a 4 week old male mouse. BAG3 expression was detected at highest levels in skeletal (quadriceps and diaphragm) and smooth (heart) muscle specimens.
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry of formalin-fixed paraffin-embedded human pancreas tissue sections. Using BAG3 polyclonal antibody (Cat # PAB0330) at 1 : 2000. A, normal pancreas. B and C, pancreatic cancer. Hematoxylin-eosin counterstain.
  • Immunohistochemistry (Frozen sections)
  • Immunohistochemistry (Frozen sections)
  • Frozen mouse muscle tissue section stained for BAG3 expression using BAG3 polyclonal antibody (Cat # PAB0330) at 1 : 2000. The tissue section was fixed in 3.8% paraformaldehyde prior to staining. BAG3 localizes with Z-disk proteins.
  • Immunoprecipitation
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Immunohistochemistry (Frozen sections)
  • Immunohistochemistry (Frozen sections)
  • enlarge
  • Immunoprecipitation
  • Gene Information
  • Entrez GeneID:
  • 9531
  • Gene Name:
  • BAG3
  • Gene Alias:
  • BAG-3,BIS,CAIR-1,MGC104307
  • Gene Description:
  • BCL2-associated athanogene 3
  • Gene Summary:
  • BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The protein encoded by this gene contains a WW domain in the N-terminal region and a BAG domain in the C-terminal region. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. [provided by RefSeq
  • Other Designations:
  • BAG-family molecular chaperone regulator-3,BCL2-binding athanogene 3,Bcl-2-binding protein,OTTHUMP00000020599,docking protein CAIR-1
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