BAG3 recombinant monoclonal antibody, clone 3D8
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
Western Blot
Western blot analysis of Lane 1: Hela whole cell lysate, Lane 2: 293 whole cell lysate, Lane 3: A549 whole cell lysate, Lane 4: HepG2 whole cell lysate and Lane 5: U87 whole cell lysate with BAG3 recombinant monoclonal antibody, clone 3D8 (Cat # RAB04377).
Immunohistochemistry
Immunohistochemical staining of human breast cancer with BAG3 recombinant monoclonal antibody, clone 3D8 (Cat # RAB04377) (diluated at 1:73.75).
-
Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human BAG3.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against a synthetic peptide corresponding to human BAG3.
Theoretical MW (kDa)
Calculated MW: 62 kD
Reactivity
Human
Form
Liquid
Purification
Affinity chromatography
Isotype
IgG
Recommend Usage
ELISA
Immunohistochemistry (1:50-1:200)
Western Blot (1:500-1:5000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH7.4 (150 mM NaCl, 50% glycerol and 0.02% sodium azide)
Storage Instruction
Store at -20°C or -80°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Applications
Western Blot
Western blot analysis of Lane 1: Hela whole cell lysate, Lane 2: 293 whole cell lysate, Lane 3: A549 whole cell lysate, Lane 4: HepG2 whole cell lysate and Lane 5: U87 whole cell lysate with BAG3 recombinant monoclonal antibody, clone 3D8 (Cat # RAB04377).Immunohistochemistry
Immunohistochemical staining of human breast cancer with BAG3 recombinant monoclonal antibody, clone 3D8 (Cat # RAB04377) (diluated at 1:73.75).Enzyme-linked Immunoabsorbent Assay
-
Gene Info — BAG3
Entrez GeneID
9531Protein Accession#
O95817Gene Name
BAG3
Gene Alias
BAG-3, BIS, CAIR-1, MGC104307
Gene Description
BCL2-associated athanogene 3
Omim ID
603883Gene Ontology
HyperlinkGene Summary
BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The protein encoded by this gene contains a WW domain in the N-terminal region and a BAG domain in the C-terminal region. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. [provided by RefSeq
Other Designations
BAG-family molecular chaperone regulator-3|BCL2-binding athanogene 3|Bcl-2-binding protein|OTTHUMP00000020599|docking protein CAIR-1
-
Interactome
-
Disease
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com