CCL17 (Human) Recombinant Protein
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Specification
Product Description
Human CCL17 (Q92583, 24 a.a. - 94 a.a.) partial recombinant protein expressed in Escherichia coli.
Sequence
ARGTNVGRECCLEYFKGAIPLRKLKTWYQTSEDCSRDAIVFVTVQGRAICSDPNNKRVKNAVKYLQSLERS
Host
Escherichia coli
Theoretical MW (kDa)
8.1
Form
Lyophilized
Preparation Method
Escherichia coli expression system
Purity
> 97% by SDS-PAGE
Endotoxin Level
< 1 EU per 1 ug of protein (determined by LAL method)
Activity
The biological activity determined by a chemotaxis bioassay using human T-lymphocytes is in a concentration range of 1.0 - 10.0 ng/ml.
Storage Buffer
Lyophilized from sterile distilled Water up to 0.1 - 1.0 mg/ml
Storage Instruction
Store at 4°C to 8°C for 1 week. For long term storage store at -20°C to -80°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Functional Study
SDS-PAGE
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Gene Info — CCL17
Entrez GeneID
6361Protein Accession#
Q92583Gene Name
CCL17
Gene Alias
A-152E5.3, ABCD-2, MGC138271, MGC138273, SCYA17, TARC
Gene Description
chemokine (C-C motif) ligand 17
Omim ID
601520Gene Ontology
HyperlinkGene Summary
This gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 16. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for T lymphocytes, but not monocytes or granulocytes. The product of this gene binds to chemokine receptors CCR4 and CCR8. This chemokine plays important roles in T cell development in thymus as well as in trafficking and activation of mature T cells. [provided by RefSeq
Other Designations
OTTHUMP00000164673|T cell-directed CC chemokine|small inducible cytokine A17|small inducible cytokine subfamily A (Cys-Cys), member 17|thymus and activation-regulated chemokine
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