CCL17 (Human) Recombinant Protein
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Specification
Product Description
Human CCL17 (Q92583, 24 a.a. - 94 a.a.) partial recombinant protein expressed in Escherichia coli.
Sequence
ARGTNVGRECCLEYFKGAIPLRKLKTWYQTSEDCSRDAIVFVTVQGRAICSDPNNKRVKNAVKYLQSLERS
Host
Escherichia coli
Theoretical MW (kDa)
8
Form
Lyophilized
Preparation Method
Escherichia coli expression system
Purification
Ion exchange column and HPLC reverse phase column
Purity
> 90% by SDS-PAGE and HPLC
Endotoxin Level
< 0.1 ng/ug (1 EU/ug)
Activity
Determined by the ability to chemoattract human T cells using a concentration range of 2.0-40.0 ng/mL.
Storage Buffer
Lyophilized from 20 mM PB, 100 mM NaCl, pH 7.5
Storage Instruction
Store at -20°C on dry atmosphere for 2 years.
After reconstitution with deionized water, store at 4°C for 1 month or store at -20°C for 6 months.
Aliquot to avoid repeated freezing and thawing. -
Applications
Functional Study
SDS-PAGE
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Gene Info — CCL17
Entrez GeneID
6361Protein Accession#
Q92583Gene Name
CCL17
Gene Alias
A-152E5.3, ABCD-2, MGC138271, MGC138273, SCYA17, TARC
Gene Description
chemokine (C-C motif) ligand 17
Omim ID
601520Gene Ontology
HyperlinkGene Summary
This gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 16. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for T lymphocytes, but not monocytes or granulocytes. The product of this gene binds to chemokine receptors CCR4 and CCR8. This chemokine plays important roles in T cell development in thymus as well as in trafficking and activation of mature T cells. [provided by RefSeq
Other Designations
OTTHUMP00000164673|T cell-directed CC chemokine|small inducible cytokine A17|small inducible cytokine subfamily A (Cys-Cys), member 17|thymus and activation-regulated chemokine
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