IL3RA (Human) Recombinant Protein

Catalog # P6767

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Price

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Quantity

Size:100 ug
Price: USD $ 531.00
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Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
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QC Test

IL3RA (Human) Recombinant Protein (Cat #P6767) was determined by SDS-PAGE with Coomassie Blue, showing a band at 145-150kDa.

Result of activity analysis
Note

Result of activity analysis

Result of activity analysis

  • Specification

    Product Description

    Human IL3RA (NP_002174.1, 20 a.a. - 305 a.a.) partial recombinant protein with His tag at C-terminus expressed in HEK293 cells.Bioactive Protein,Bioactive Proteins,Bioactive,Active,Functional Protein,Functional Proteins,Recombinant Human Protein,Recombinant Human Proteins,Human Recombinant Protein,Human Recombinant Proteins,HuPro

    Host

    Human

    Theoretical MW (kDa)

    145-150

    Form

    Lyophilized

    Preparation Method

    Mammalian cell (HEK293) expression system

    Purification

    Ni-sepharose purification

    Purity

    > 90% by SDS-PAGE

    Endotoxin Level

    < 0.1 EU/ug

    Activity

    Measured by the binding ability in a functional ELISA. Immobilized recombinant Human IL3 at 4 ug/mL (100 uL/well) can bind recombinant Human IL3RA, the EC50 of Human IL3RA is 5.3 ug/mL.

    Quality Control Testing

    SDS-PAGE Stained with Coomassie Blue

    IL3RA (Human) Recombinant Protein (Cat #P6767) was determined by SDS-PAGE with Coomassie Blue, showing a band at 145-150kDa.

    Recommend Usage

    SDS-PAGE
    The optimal working dilution should be determined by the end user.

    Storage Buffer

    Lyophilized from PBS, pH 7.4.

    Storage Instruction

    Store the lyophilized protein at -20°C to -80°C for long term.
    After reconstitution to a concentration of 0.1-0.5 mg/mL in sterile distilled water, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
    Aliquot to avoid repeated freezing and thawing.

    Note

    Result of activity analysis

  • Applications

    SDS-PAGE

  • Gene Info — IL3RA

    Entrez GeneID

    3563

    Protein Accession#

    P26951

    Gene Name

    IL3RA

    Gene Alias

    CD123, IL3R, IL3RAY, IL3RX, IL3RY, MGC34174, hIL-3Ra

    Gene Description

    interleukin 3 receptor, alpha (low affinity)

    Omim ID

    308385 430000

    Gene Ontology

    Hyperlink

    Gene Summary

    The protein encoded by this gene is an interleukin 3 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL3 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL3. This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain (CSF2RA) form a cytokine receptor gene cluster in a X-Y pseudoautosomal region on chromosomes X or Y. [provided by RefSeq

    Other Designations

    CD123 antigen|Interleukin-3 receptor|OTTHUMP00000022828|interleukin 3 receptor, alpha

  • Interactome
  • Pathway
  • Disease
Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
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