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PIP4K2A (Human) Recombinant Protein BioActive

  • Catalog # : P6571
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  • Specification
  • Product Description:
  • Human PIP4K2A (NP_005019, 1 a.a. - 406 a.a.) full length recombinant protein with GST-tag at N-terminal using baculovirus expression system.
  • Host:
  • Viruses
  • Form:
  • Liquid
  • Preparation Method:
  • Baculovirus expression system.
  • Purification:
  • Glutathione sepharose chromatography.
  • Purity:
  • 0.95
  • Activity:
  • The activity was determined by ADP-Glo Assay. The enzyme was incubated with Lipid substrate and Mn/ATP. The phosphorylation was detected by the ADP-Glo Kinase Assay technology (luminescent ADP detection assay). Substrate: PI (5) P and Phosphatidylserine, ATP: 100 uM.
  • Quality Control Testing:
  • The purity was assessed by SDS-PAGE/CBB staining.
  • Storage Buffer:
  • 50 mM Tris-HCl, 150 mM NaCl, 0.05% Brij35, 1 mM DTT, 10% glycerol, pH7.5
  • Storage Instruction:
  • Stored at -80°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • Result of activity analysis

  • Applications
  • Functional Study
  • Application Image
  • Functional Study
  • Gene Information
  • Entrez GeneID:
  • 5305
  • Gene Name:
  • PIP4K2A
  • Gene Alias:
  • FLJ13267,PI5P4KA,PIP5K2A,PIP5KII-alpha,PIP5KIIA,PIPK
  • Gene Description:
  • phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
  • Gene Summary:
  • Phosphatidylinositol-5,4-bisphosphate, the precursor to second messengers of the phosphoinositide signal transduction pathways, is thought to be involved in the regulation of secretion, cell proliferation, differentiation, and motility. The protein encoded by this gene is one of a family of enzymes capable of catalyzing the phosphorylation of phosphatidylinositol-5-phosphate on the fourth hydroxyl of the myo-inositol ring to form phosphatidylinositol-5,4-bisphosphate. The amino acid sequence of this enzyme does not show homology to other kinases, but the recombinant protein does exhibit kinase activity. This gene is a member of the phosphatidylinositol-5-phosphate 4-kinase family. [provided by RefSeq
  • Other Designations:
  • 1-phosphatidylinositol-4-phosphate kinase,1-phosphatidylinositol-4-phosphate-5-kinase,OTTHUMP00000019300,OTTHUMP00000043353,PIP5KIIalpha,PtdIns(4)P-5-kinase B isoform,diphosphoinositide kinase,phosphatidylinositol-4-phosphate 5-kinase, type II, alpha,type
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