PIP5K2A (Human) Recombinant Protein (P01)
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Specification
Product Description
Human PIP5K2A full-length ORF ( AAH18034, 1 a.a. - 406 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MATPGNLGSSVLASKTKTKKKHFVAQKVKLFRASDPLLSVLMWGVNHSINELSHVQIPVMLMPDDFKAYSKIKVDNHLFNKENMPSHFKFKEYCPMVFRNLRERFGIDDQDFQNSLTRSAPLPNDSQARSGARFHTSYDKRYIIKTITSEDVAEMHNILKKYHQYIVECHGITLLPQFLGMYRLNVDGVEIYVIVTRNVFSHRLSVYRKYDLKGSTVAREASDKEKAKELPTLKDNDFINEGQKIYIDDNNKKVFLEKLKKDVEFLAQLKLMDYSLLVGIHDVERAEQEEVECEENDGEEEGESDGTHPVGTPPDSPGNTLNSSPPLAPGEFDPNIDVYGIKCHENSPRKEVYFMAIIDILTHYDAKKKAAHAAKTVKHGAGAEISTVNPEQYSKRFLDFIGHILT
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
70.40
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — PIP4K2A
Entrez GeneID
5305GeneBank Accession#
BC018034Protein Accession#
AAH18034Gene Name
PIP4K2A
Gene Alias
FLJ13267, PI5P4KA, PIP5K2A, PIP5KII-alpha, PIP5KIIA, PIPK
Gene Description
phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
Omim ID
603140Gene Ontology
HyperlinkGene Summary
Phosphatidylinositol-5,4-bisphosphate, the precursor to second messengers of the phosphoinositide signal transduction pathways, is thought to be involved in the regulation of secretion, cell proliferation, differentiation, and motility. The protein encoded by this gene is one of a family of enzymes capable of catalyzing the phosphorylation of phosphatidylinositol-5-phosphate on the fourth hydroxyl of the myo-inositol ring to form phosphatidylinositol-5,4-bisphosphate. The amino acid sequence of this enzyme does not show homology to other kinases, but the recombinant protein does exhibit kinase activity. This gene is a member of the phosphatidylinositol-5-phosphate 4-kinase family. [provided by RefSeq
Other Designations
1-phosphatidylinositol-4-phosphate kinase|1-phosphatidylinositol-4-phosphate-5-kinase|OTTHUMP00000019300|OTTHUMP00000043353|PIP5KIIalpha|PtdIns(4)P-5-kinase B isoform|diphosphoinositide kinase|phosphatidylinositol-4-phosphate 5-kinase, type II, alpha|type
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Disease
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