TNFRSF13B (Human) Recombinant Protein
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Specification
Product Description
Human TNFRSF13B (O14836) recombinant protein expressed in E. Coli.
Sequence
SGLGRSRRGGRSRVDQEERFPQGLWTGVAMRSCPEEQYWDPLLGTCMSCKTICNHQSQRTCAAFCRSLSCRKEQGKFYDHLLRDCISCASICGQHPKQCAYFCENKLRSPVNLPPELRRQRSGEVENNSDNSGRYQGLEHRGSEASPALPGLKLSADQV
Host
Escherichia coli
Theoretical MW (kDa)
17
Form
Lyophilized
Purity
> 98%
Endotoxin Level
<= 1 EUs/ug (LAL gel clot method)
Activity
Determined by the ability to block human BAFF induced T2B cell survival using a concentration range of 1-3 ug/mL.
Storage Buffer
Lyophilized from PBS, pH 7.2.
Storage Instruction
Stored at -20°C to-80°C.
After reconstitution with sterile water not less than 0.1 mg/mL, store at -20°C to -80°C for 6 months, store at 4°C for 1 month.
Aliquot to avoid repeated freezing and thawing. -
Applications
Western Blot
Functional Study
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Gene Info — TNFRSF13B
Entrez GeneID
23495Protein Accession#
O14836Gene Name
TNFRSF13B
Gene Alias
CD267, CVID, FLJ39942, MGC133214, MGC39952, TACI, TNFRSF14B
Gene Description
tumor necrosis factor receptor superfamily, member 13B
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a lymphocyte-specific member of the tumor necrosis factor (TNF) receptor superfamily. It interacts with calcium-modulator and cyclophilin ligand (CAML). The protein induces activation of the transcription factors NFAT, AP1, and NF-kappa-B and plays a crucial role in humoral immunity by interacting with a TNF ligand. This gene is located within the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq
Other Designations
OTTHUMP00000065442|transmembrane activator and CAML interactor|tumor necrosis factor receptor 13B
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