ATOX1 (Human) Recombinant Protein
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Specifications
Product Description
Human ATOX1 (NP_004036.1) full-length recombinant protein expressed in yeast.
Sequence
MPKHEFSVDMTCGGCAEAVSRVLNKLGGVKYDIDLPNKKVCIESEHSMDTLLATLKKTGKTVSYLGLE
Host
Yeast
Theoretical MW (kDa)
7.39
Form
Liquid
Preparation Method
Yeast expression system
Purification
Affinity Purification
Purity
90%
Storage Buffer
In 50 mM HEPES, 100mM NaCl, pH 7.5 (30% glycerol, 30 mM Glutathione, 0.5% TritonX-100, 1 mM dithiothreitol)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
SDS-PAGE
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Gene Info — ATOX1
Entrez GeneID
475Protein Accession#
NP_004036.1Gene Name
ATOX1
Gene Alias
ATX1, HAH1, MGC138453, MGC138455
Gene Description
ATX1 antioxidant protein 1 homolog (yeast)
Omim ID
602270Gene Ontology
HyperlinkGene Summary
This gene encodes a copper chaperone that plays a role in copper homeostasis by binding and transporting cytosolic copper to ATPase proteins in the trans-Golgi network for later incorporation to the ceruloplasmin. This protein also functions as an antioxidant against superoxide and hydrogen peroxide, and therefore, may play a significant role in cancer carcinogenesis. Because of its cytogenetic location, this gene represents a candidate gene for 5q-syndrome. [provided by RefSeq
Other Designations
antioxidant protein 1|copper transport protein|metal transport protein
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Interactomes
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