CXCL10 (Human) Recombinant Protein
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Specification
Product Description
Human CXCL10 (P02778, 22 a.a. - 98 a.a.) partial recombinant protein expressed in Escherichia coli.
Sequence
VPLSRTVRCTCISISNQPVNPRSLEKLEIIPASQFCPRVEIIATMKKKGEKRCLNPESKAIKNLLKAVSKERSKRSP
Host
Escherichia coli
Theoretical MW (kDa)
9
Form
Lyophilized
Preparation Method
Escherichia coli expression system
Purification
Ion exchange column and HPLC reverse phase column
Purity
> 90% by SDS-PAGE and HPLC
Endotoxin Level
< 0.1 ng/ug (1 EU/ug)
Activity
Determined by the ability to chemoattract human T-Lymphocytes using a concentration of 10-50 ng/mL.
Storage Buffer
Lyophilized from PBS, pH 7.0
Storage Instruction
Store at -20°C on dry atmosphere for 2 years.
After reconstitution with deionized water, store at 4°C for 1 month or store at -20°C for 6 months.
Aliquot to avoid repeated freezing and thawing. -
Applications
Functional Study
SDS-PAGE
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Gene Info — CXCL10
Entrez GeneID
3627Protein Accession#
P02778Gene Name
CXCL10
Gene Alias
C7, IFI10, INP10, IP-10, SCYB10, crg-2, gIP-10, mob-1
Gene Description
chemokine (C-X-C motif) ligand 10
Omim ID
147310Gene Ontology
HyperlinkGene Summary
This gene encodes a chemokine of the CXC subfamily and ligand for the receptor CXCR3. Binding of this protein to CXCR3 results in pleiotropic effects, including stimulation of monocytes, natural killer and T-cell migration, and modulation of adhesion molecule expression. [provided by RefSeq
Other Designations
gamma IP10|interferon-inducible cytokine IP-10|protein 10 from interferon (gamma)-induced cell line|small inducible cytokine B10|small inducible cytokine subfamily B (Cys-X-Cys), member 10
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