NP monoclonal antibody, clone 11
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant NP.
Immunogen
Recombinant protein corresponding to amino acids 68-289 of human NP.
Host
Mouse
Reactivity
Human
Specificity
It can expression in HEK293 whole cell lysate.
Form
Liquid
Purification
Affinity purification
Isotype
IgG2a
Recommend Usage
Western blot (1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In Citrate-Tris-HCl buffer, pH 7.0 (0.02% Proclin 300)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Western Blot (Cell lysate)
Western blot analysis of HEK293 whole cell lystae with NP monoclonal antibody, clone 11 (Cat # MAB9881) at 1:1000 dilution.Enzyme-linked Immunoabsorbent Assay
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Gene Info — NP
Entrez GeneID
4860GeneBank Accession#
NM_000270.2Protein Accession#
NP_000261.2Gene Name
NP
Gene Alias
FLJ94043, FLJ97288, FLJ97312, MGC117396, MGC125915, MGC125916, PNP, PRO1837, PUNP
Gene Description
nucleoside phosphorylase
Omim ID
164050Gene Ontology
HyperlinkGene Summary
This gene encodes an enzyme which reversibly catalyzes the phosphorolysis of purine nucleosides. The enzyme is trimeric, containing three identical subunits. Mutations which result in nucleoside phosphorylase deficiency result in defective T-cell (cell-mediated) immunity but can also affect B-cell immunity and antibody responses. Neurologic disorders may also be apparent in patients with immune defects. A known polymorphism at aa position 51 that does not affect enzyme activity has been described. A pseudogene has been identified on chromosome 2. [provided by RefSeq
Other Designations
inosine phosphorylase|purine nucleoside phosphorylase
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Interactome
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Pathway
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Disease
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