NP polyclonal antibody (A01)
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Specification
Product Description
Mouse polyclonal antibody raised against a partial recombinant NP.
Immunogen
NP (NP_000261, 174 a.a. ~ 283 a.a) partial recombinant protein with GST tag.
Sequence
ALSTWKQMGEQRELQEGTYVMVAGPSFETVAECRVLQKLGADAVGMSTVPEVIVARHCGLRVFGFSLITNKVIMDYESLEKANHEEVLAAGKQAAQKLEQFVSILMASIP
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (85); Rat (77)
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (38.21 KDa) .
Storage Buffer
50 % glycerol
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
NP polyclonal antibody (A01), Lot # 051017JC01 Western Blot analysis of NP expression in Jurkat ( Cat # L017V1 ).Western Blot (Recombinant protein)
ELISA
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Gene Info — NP
Entrez GeneID
4860GeneBank Accession#
NM_000270Protein Accession#
NP_000261Gene Name
NP
Gene Alias
FLJ94043, FLJ97288, FLJ97312, MGC117396, MGC125915, MGC125916, PNP, PRO1837, PUNP
Gene Description
nucleoside phosphorylase
Omim ID
164050Gene Ontology
HyperlinkGene Summary
This gene encodes an enzyme which reversibly catalyzes the phosphorolysis of purine nucleosides. The enzyme is trimeric, containing three identical subunits. Mutations which result in nucleoside phosphorylase deficiency result in defective T-cell (cell-mediated) immunity but can also affect B-cell immunity and antibody responses. Neurologic disorders may also be apparent in patients with immune defects. A known polymorphism at aa position 51 that does not affect enzyme activity has been described. A pseudogene has been identified on chromosome 2. [provided by RefSeq
Other Designations
inosine phosphorylase|purine nucleoside phosphorylase
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Interactome
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Pathway
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Disease
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